Donate to Cancer Research, Earn Up to 50X AAdvantage<sup>®</sup> Miles Donate to Cancer Research, Earn Up to 50X AAdvantage<sup>®</sup> Miles

Donate to Cancer Research, Earn Up to 50X AAdvantage® Miles

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Update 8/20/2025: That was quick! Donations to Stand Up To Cancer through this promotion have already reached $3,000,000. That's great news for cancer research. However, it means that donors will only earn 25X AAdvantage® miles per dollar spent on further donations.

American Airlines just relaunched its annual promotion to offer bonus miles on Stand Up To Cancer donations. Now through September 30, 2025, AAdvantage members will earn at least 25 miles on the dollar for all Stand Up To Cancer donations over $25. And you'll earn a whopping 50X miles when making a donation using an AAdvantage co-branded Mastercard — until $3 million has been donated.

Here's how to donate and get your bonus miles.

AAdvantage Miles for Stand Up To Cancer Donations

From August 15 to September 30, 2025, eligible donations made to Stand Up To Cancer can earn even more AAdvantage miles. AAdvantage members typically earn 10 miles per dollar donated to Stand Up To Cancer. But, for the next one and a half months, AAdvantage members will receive at least 25 miles for every dollar donated when donating at least $25 and listing their AAdvantage number at the time of donation.

Even better, AAdvantage members who use their U.S.-issued American Airlines AAdvantage Mastercard to make the donation will receive double. That's 50 miles for every dollar donated!

Bonus AA miles promotion for Stand Up To Cancer
Screenshot of Stand Up To Cancer website

The terms and conditions don't list eligible cards. But all AAdvantage co-branded Mastercard-branded cards should qualify, including:

Stand Up To Cancer bonus miles promo
Screenshot of Stand Up To Cancer website

To earn bonus miles, you'll need to donate at least $25. After that, you can donate at any whole dollar amount, up to a maximum of $10,000. A donation of $25 will earn 625 AAdvantage miles, while a $100 donation earns 2,500 miles.

If you charge your donation to an American Airlines AAdvantage Mastercard, your miles will be doubled:

  • $25 donation = 1,250 miles
  • $50 donation = 2,500 miles
  • $100 donation = 5,000 miles

To make your donation, click here.

Terms and Conditions

  • These are considered bonus miles, so they don't count as Loyalty Points toward status qualification.
  • Bonus ends on September 30, 2025 — or when donations reach a combined $3,000,000.
  • Bonus miles will be deposited in your AAdvantage account by December 19, 2025.
  • Donations can only be accepted in U.S. dollars.
  • Donations through this promotion are non-refundable.
  • Each mile is valued at 3 cents per mile for charitable deduction purposes. The receipt of miles may reduce the tax deductibility of your contribution.

What Is Stand Up To Cancer?

Stand Up To Cancer is a charitable program that has been collecting donations for cancer research since 2008. Since then, it's raised hundreds of millions of dollars, primarily through online and televised efforts. One of the first telethons in 2008 was broadcast to over 170 countries and raised over $100 million. 100% of funds raised are forwarded to and distributed by the American Association for Cancer Research.

Our Take

This is a great promotion, considering you can effectively buy AAdvantage miles at 2 cents each. That's less than the 2.45 cents each through the ongoing American Airlines buy miles promotion. And this is a great way to gain a nice chunk of miles for your donations if you're a fan of donating to cancer research. And if you're just looking at buying more AAdvantage miles, this is currently your best chance to do so.

Some American Airlines AAdvantage awards cost as little as 5,000 miles. You'd only need to donate $100 using an American Airlines AAdvantage Mastercard to earn enough miles to book such an award. That's nothing short of a win-win.

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